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Commitments and Contingencies - Additional Information (Detail)

v3.21.1
Commitments and Contingencies - Additional Information (Detail)
 1 Months Ended 12 Months Ended
Apr. 01, 2014
USD ($)
$ / shares
shares
Mar. 02, 2012
USD ($)
Jun. 18, 2010
USD ($)
shares
Jun. 08, 2010
USD ($)
shares
Jun. 30, 2018
USD ($)
Apr. 30, 2018
USD ($)
Dec. 31, 2020
USD ($)
$ / shares
shares
Dec. 31, 2019
shares
Commitments and Contingencies Disclosure [Line Items]                
Total lease obligation         $ 54,000      
Operating lease, term of contract         1 year      
Operating leases description         The total lease obligation was $54,000, payable in 12 equal monthly installments commencing August 1, 2018. Since the end of the one-year initial term on July 31, 2019, the lease continues on a month-to-month basis.      
Emory University License Agreements                
Commitments and Contingencies Disclosure [Line Items]                
License agreements, fair value of shares issued       $ 313,500        
Number of license agreements       2        
License agreement description       License A term is the later of 10 years or until the expiration of the patent rights. License B was terminated in May 2013 under the normal course of business.        
Shares forfeited or returned             $ 0  
Potential milestone payments             280,000  
Emory University License Agreements | License A                
Commitments and Contingencies Disclosure [Line Items]                
License agreements, shares issued | shares       393,370        
License agreement, term       10 years        
Emory University License Agreements | License B                
Commitments and Contingencies Disclosure [Line Items]                
License agreements, shares issued | shares       437,078        
Duke University License Agreement                
Commitments and Contingencies Disclosure [Line Items]                
License agreements, shares issued | shares     611,909          
License agreements, fair value of shares issued     $ 247,500          
License agreement description     Unless sooner terminated as provided elsewhere in the agreement, the Duke License term is the later of 10 years or until the expiration of the patent rights (see below).          
License agreement, term     10 years          
Potential milestone payments             $ 280,000  
License termination date             Apr. 16, 2020  
License termination cost             $ 0  
Sphaera Agreement [Member]                
Commitments and Contingencies Disclosure [Line Items]                
Potential milestone payments             5,625,000  
License agreement, fixed fee paid   $ 160,000            
Milestone payment   $ 0            
CEO | 2020 CEO Employment Agreement                
Commitments and Contingencies Disclosure [Line Items]                
Annual base salary             $ 455,000  
Annual performance cash bonus, as percentage of annual base salary, based upon achievement of performance goals established by the compensation committee of the board of directors             35.00%  
CEO | 2020 CEO Employment Agreement | Common Stock                
Commitments and Contingencies Disclosure [Line Items]                
Stock option granted | shares             100,000  
Stock option granted, exercise price | $ / shares             $ 10.00  
Stock option granted, vesting period             3 years  
CEO | 2014 CEO Agreement                
Commitments and Contingencies Disclosure [Line Items]                
Annual base salary $ 224,000           $ 292,800  
CEO | 2014 CEO Agreement | Common Stock                
Commitments and Contingencies Disclosure [Line Items]                
Stock option granted | shares 43,708             196,685
Stock option granted, exercise price | $ / shares $ 0.38              
Stock option granted, vesting period 10 years              
CEO | 2014 CEO Agreement | Common Stock | Annual Grants [Member]                
Commitments and Contingencies Disclosure [Line Items]                
Stock option granted | shares 21,854              
CFO | 2020 CFO Employment Agreement                
Commitments and Contingencies Disclosure [Line Items]                
Annual base salary             $ 375,000  
Annual performance cash bonus, as percentage of annual base salary, based upon achievement of performance goals established by the compensation committee of the board of directors             30.00%  
CFO | 2020 CFO Employment Agreement | Common Stock                
Commitments and Contingencies Disclosure [Line Items]                
Stock option granted | shares             100,000  
Stock option granted, exercise price | $ / shares             $ 10.00  
Stock option granted, vesting period             3 years  
CFO | 2018 CFO Consulting Agreement                
Commitments and Contingencies Disclosure [Line Items]                
Consulting services fee per month           $ 12,500    
CFO | 2018 CFO Consulting Agreement | Convertible Revolving Demand Promissory Note                
Commitments and Contingencies Disclosure [Line Items]                
Consulting services fee accrued           $ 12,500