Commitments and Contingencies (Additional Information) (Details)
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1 Months Ended |
3 Months Ended |
9 Months Ended |
12 Months Ended |
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Apr. 18, 2022 |
Mar. 31, 2022
USD ($)
shares
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Dec. 31, 2020
USD ($)
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Aug. 01, 2018
USD ($)
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Apr. 01, 2014
USD ($)
$ / shares
shares
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Jun. 18, 2010
USD ($)
shares
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Jun. 08, 2010
USD ($)
Agreements
shares
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Apr. 30, 2018
USD ($)
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Sep. 30, 2022
USD ($)
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Sep. 30, 2022
USD ($)
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Dec. 31, 2021
USD ($)
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Dec. 31, 2020
USD ($)
$ / shares
shares
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Dec. 31, 2019
shares
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Jun. 30, 2018 |
Loss Contingencies [Line Items] |
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Right-of-use asset |
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$ 353,250
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$ 353,250
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Operating Lease, Liability, Current |
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142,048
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142,048
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Operating Lease, Liability, Noncurrent |
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232,020
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232,020
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Lease Expense |
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20,818
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20,818
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Operating lease Obligation |
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374,068
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374,068
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Stock option granted, exercise price | $ / shares |
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$ 0.38
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$ 10
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Total potential milestone payments |
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$ 5,625,000
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Operating lease, term of contract |
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1 year
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Lease obligation |
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$ 54,000
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Operating leases description |
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The total lease obligation was $54,000, payable in 12 equal monthly installments commencing August 1, 2018. Since the end of the one-year initial term on July 31, 2019, the lease continues on a month-to-month basis.
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Lease obligation payable monthly installments |
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12 equal monthly installments
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2020 CEO Agreement |
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Loss Contingencies [Line Items] |
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Annual base salary |
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$ 455,000
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Stock option granted | shares |
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100,000
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Percentage of annual base salary |
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35.00%
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Stock option granted, vesting period |
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3 years
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2014 CEO Agreement |
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Loss Contingencies [Line Items] |
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Annual base salary |
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$ 224,000
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$ 292,800
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Stock option granted | shares |
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43,708
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21,854
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196,685
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Stock option granted, vesting period |
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10 years
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12 months
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2018 Flagship Agreement |
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Loss Contingencies [Line Items] |
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Consulting services fee per month |
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$ 12,500
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Consulting services fee accrued |
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$ 12,500
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Maturity description |
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The 2018 Flagship Agreement ended on December 31, 2020 and the Frattaroli Employment Agreement superseded the 2018 Flagship Agreement in all respects on January 1, 2021.
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Emory University License Agreements |
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Loss Contingencies [Line Items] |
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License agreements, fair value of shares issued |
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$ 313,500
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Total potential milestone payments |
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$ 280,000
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Number of license agreements | Agreements |
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2
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License agreement description |
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the License A term is the later of 10 years or until the expiration of the patent rights. License B was terminated in May 2013 under the normal course of business.
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Emory University License Agreements | License A [Member] |
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Loss Contingencies [Line Items] |
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License agreements, shares issued | shares |
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393,370
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License agreement, term |
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10 years
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Emory University License Agreements | License B [Member] |
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Loss Contingencies [Line Items] |
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License agreements, fair value of shares issued |
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$ 437,078
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Duke University License Agreement |
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Loss Contingencies [Line Items] |
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License agreements, shares issued | shares |
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611,909
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License agreements, fair value of shares issued |
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$ 247,500
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Total potential milestone payments |
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$ 0
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$ 280,000
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$ 0
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License agreement, term |
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10 years
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License termination date |
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April 16, 2020
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License termination cost |
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$ 0
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Sphaera Agreement |
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Loss Contingencies [Line Items] |
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License agreement, fixed fee paid |
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$ 160,000
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Frattaroli Employment Agreement |
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Loss Contingencies [Line Items] |
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Annual base salary |
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$ 375,000
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Stock option granted | shares |
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100,000
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Percentage of annual base salary |
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30.00%
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Stock option granted, vesting period |
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3 years
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Prepaid Expenses and Other Current Assets [Member] |
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Loss Contingencies [Line Items] |
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Security deposit |
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$ 25,000
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$ 25,000
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Subsequent Event [Member] | 2020 CEO Agreement |
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Loss Contingencies [Line Items] |
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Annual base salary |
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$ 510,000
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Stock option granted | shares |
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125,000
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Percentage of annual base salary |
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50.00%
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Stock option granted, vesting period |
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3 years
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Subsequent Event [Member] | Frattaroli Employment Agreement |
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Loss Contingencies [Line Items] |
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Annual base salary |
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$ 400,000
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Percentage of annual base salary |
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40.00%
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Lexington [Member] |
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Loss Contingencies [Line Items] |
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Lessee, Operating Lease, Discount Rate |
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12.00%
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12.00%
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Right-of-use asset |
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$ 353,350
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$ 353,350
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Lease Expiration Date |
Jul. 31, 2025
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Lessor, Operating Lease, Description |
The Office Lease contains escalating payments during the lease period. Upon execution of the Office Lease, the Company prepaid one month of rent and a security deposit, one of which will be held in escrow and credited at the termination of the lease and the other of which will be applied to the first month’s rent.
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